An Impartial Approach to Partial Agonism: A Buprenorphine Review

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Buprenorphine is perhaps the most highly misunderstood medication of our time, or at least within the pain management pharmacological treatment options. Being utilized within the indications of pain management and opioid use disorder (opioid addiction) certainly propels it to the top of any polarized discussions to say the least. So how does one navigate through the pharma-sea of opinions? Join us for a dynamic discussion on the complicated simplicities of buprenorphine pharmacology including partial mu opioid agonism, mu opioid receptor affinity, half-life related dosage selections, CYP-450 metabolism and respective interactions, maximum dosage recommendations, morphine milligram equivalent (MME) calculations, and the infamous respiratory depression relative ceiling effects. Dispelling every rumor, one pharmacological principal at a time, helping you help your patients every day.

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Course Information

Target Audience

Pharmacist

Pharmacy Technician

Knowledge Level

General Overview

This activity will apply to a broad range of learning needs/pharmacy settings. It may include common disease state/therapy overivews and/or general pharmacy needs such as medication errors, immunizations, or law topics.

Learning Objectives

Pharmacist

Pharmacist

  • Differentiate buprenorphine prescription products by FDA approved indications for pain management and opioid use disorder.
  • Describe buprenorphine’s atypical prescription opioid mechanism of action as a partial mu opioid agonist with greater than average mu opioid receptor affinity and relative respiratory depression ceiling effect.
  • Recall buprenorphine’s pharmacological properties relevant to patient care including CYP-3A4 interactions, long half-life, maximum recommended dosage, and morphine milligram equivalency.

Pharmacy Technician

Pharmacy Technician

  • Differentiate buprenorphine prescription products by FDA approved indications for pain management and opioid use disorder.
  • Describe buprenorphine’s atypical prescription opioid mechanism of action as a partial mu opioid agonist with greater than average mu opioid receptor affinity and relative respiratory depression ceiling effect.
  • Recall buprenorphine’s pharmacological properties relevant to patient care including CYP-3A4 interactions, long half-life, maximum recommended dosage, and morphine milligram equivalency.

Course Accreditation

  • Activity Type:
    Application
  • Financial Support By:
    PharmCon
  • CE Broker
    20-858843
  • Universal Activity Number:
    Pharmacy Technician : 0798-0000-21-227-H08-T
    Pharmacist : 0798-0000-21-227-H08-P
PharmCon is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

PharmCon, Inc. is an approved course provider for continuing education for nurses by the Florida Board of Nursing. PharmCon is also recognized by the California Board of Nursing as a provider of nursing programs.

Credit for this program is issued by passing the final test hosted at www.RxConsultant.com with a score of 70% or higher.

Technology Requirements

  • Hardware Requirements
    Standard Windows/Mac System
    iPad or iPhone
    Minimum screen resolution: 1024x768
  • Software Requirements
    Standard Windows/Mac System
    iPad or iPhone
    Minimum screen resolution: 1024x768
  • Network Requirements
    Broadband Internet Connection:
    T1, Hi-speed DSL or Cable
    4G cellular connection
Computer sharing is NOT permitted due to accreditation guidelines on activity monitoring. Credit is earned by one user per device.