An Impartial Approach to Partial Agonism: A Buprenorphine Review
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Buprenorphine is perhaps the most highly misunderstood medication of our time, or at least within the pain management pharmacological treatment options. Being utilized within the indications of pain management and opioid use disorder (opioid addiction) certainly propels it to the top of any polarized discussions to say the least. So how does one navigate through the pharma-sea of opinions? Join us for a dynamic discussion on the complicated simplicities of buprenorphine pharmacology including partial mu opioid agonism, mu opioid receptor affinity, half-life related dosage selections, CYP-450 metabolism and respective interactions, maximum dosage recommendations, morphine milligram equivalent (MME) calculations, and the infamous respiratory depression relative ceiling effects. Dispelling every rumor, one pharmacological principal at a time, helping you help your patients every day.